anti-il12/fitc科研抗體產(chǎn)品
from：abcam
catalog number : byk- 0767r-fitc
quantity size : 100ug (2mg/1ml, lyophilized or liquid. buffer = 0.01m pbs, ph 7.4 with 10 mg/ml bsa and 0.1% sodium azide. reconstitute with 50ul sterile distilled water.)
background: il-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. this cytokine has pleiotropic effects in immunoregulation and inflammation. it down-regulates the expression of th1 cytokines, mhc class ii ags, and costimulatory molecules on macrophages. it also enhances b cell survival, proliferation, and antibody production. this cytokine can block nf-kappa b activity, and is involved in the regulation of the jak-stat signaling pathway. knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
also known as: il12; il-12; clmf p35; clmf1; ctl maturation factor (tcmf); cytotoxic lymphocyte maturation factor 1; cytotoxic lymphocyte maturation factor 35 kda subunit; il 12 subunit p35; il12a; interleukin 12 alpha chain; interleukin 12 p35; interleukin 12a; natural killer cell stimulatory factor 1; nk cell stimulatory factor chain 1; nksf1; p35; il12a_mouse.
specificity: -rabbit polyclonal igg, affinity purified by protein a.
-fitc conjugated
-reacts with: mouse,rat,
-immunogen:klh conjugated synthetic peptide derived from mouse il-12.
-predicted molecular weight: 22kda
application: if=1:50-200 flow-cyt=1:50-200
excitation spectrum: 490-495nm
emission spectrum: 520-530nm
not yet tested in other applications.
optimal working dilutions must be determined by the end user.
storage: store at -20 °c for one year. avoid repeated freeze/thaw
cycles. the lyophilized or liquid antibody is stable at room
temperature for at least one month and for greater than a year when
kept at -20 °c. when reconstituted in sterile ph 7.4 0.01m pbs or
diluent of antibody the antibody is stable for at least two weeks at
2-4 °c.
important note: this product as supplied is intended for research
use only, not for use in human, therapeutic or diagnostic
applications..